ZC3HC1 Antikörper

Produktnummer ABIN7121049

Produktdetails anti-ZC3HC1 Antikörper

Target: ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZC3HC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: zinc finger, C3HC-type containing 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:200-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu ZC3HC1

Target: ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))

Andere Bezeichnung: ZC3HC1 (ZC3HC1 Produkte)

Synonyme: 1110054L24Rik antikoerper, AU018540 antikoerper, AU019789 antikoerper, HSPC216 antikoerper, Nipa antikoerper, NIPA antikoerper, RGD1561099 antikoerper, zinc finger, C3HC type 1 antikoerper, zinc finger C3HC-type containing 1 antikoerper, zinc finger, C3HC-type containing 1 antikoerper, Zc3hc1 antikoerper, ZC3HC1 antikoerper

Hintergrund: Synonyms:ZC3HC1, 1110054L24Rik, hNIPA, HSPC216, NIPA Background:Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1(CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.

Molekulargewicht: 55 kDa

Gen-ID: 51530

UniProt: Q86WB0