RAN Antikörper

Produktnummer ABIN7118276

Produktdetails anti-RAN Antikörper

Target: RAN (RAN, Member RAS Oncogene Family (RAN))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: RAN, member RAS oncogene family

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu RAN

Target: RAN (RAN, Member RAS Oncogene Family (RAN))

Andere Bezeichnung: RAN (RAN Produkte)

Synonyme: ARA24 antikoerper, Gsp1 antikoerper, TC4 antikoerper, ran antikoerper, ara24 antikoerper, gsp1 antikoerper, ran-1 antikoerper, tc4 antikoerper, RAN antikoerper, RANP1 antikoerper, AAF30287 antikoerper, CG1404 antikoerper, Dmel\CG1404 antikoerper, Ran antikoerper, dran antikoerper, l(1)G0075 antikoerper, ran10A antikoerper, fc16b04 antikoerper, wu:fc16b04 antikoerper, RAN, member RAS oncogene family antikoerper, RAN, member RAS oncogene family S homeolog antikoerper, CG1404 gene product from transcript CG1404-RC antikoerper, RAN antikoerper, Ran antikoerper, ran.S antikoerper, ran antikoerper

Hintergrund: Synonyms:ARA24 Background:GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle(By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2. Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.

Molekulargewicht: 24 kDa

Gen-ID: 5901

UniProt: P62826

Pathways: Regulatorische RNA Pathways, Intracellular Steroid Hormone Receptor Signaling Pathway, Protein targeting to Nucleus