cb212 antikoerper, prc1 antikoerper, prc1l antikoerper, zgc:55982 antikoerper, zgc:86918 antikoerper, MGC68845 antikoerper, zgc:55664 antikoerper, ase1 antikoerper, ASE1 antikoerper, D7Ertd348e antikoerper, protein regulator of cytokinesis 1 antikoerper, protein regulator of cytokinesis 1a antikoerper, protein regulator of cytokinesis 1 S homeolog antikoerper, protein regulator of cytokinesis 1b antikoerper, PRC1 antikoerper, prc1a antikoerper, prc1.S antikoerper, prc1b antikoerper, CNC07120 antikoerper, prc1 antikoerper, Prc1 antikoerper
Hintergrund
Synonyms: Background:Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression(PubMed:17409436).