LILRB4 Antikörper

Produktnummer ABIN7115849

Produktdetails anti-LILRB4 Antikörper

Target: LILRB4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LILRB4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: Leukocyte immunoglobulin-like receptor subfamily B member 4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu LILRB4

Target: LILRB4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4))

Andere Bezeichnung: LILRB4 (LILRB4 Produkte)

Synonyme: CD85K antikoerper, ILT-3 antikoerper, ILT3 antikoerper, LIR-5 antikoerper, LIR5 antikoerper, Gp49b antikoerper, HM18 antikoerper, gp49 antikoerper, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 antikoerper, leukocyte immunoglobulin like receptor B4 antikoerper, leukocyte immunoglobulin-like receptor, subfamily B, member 4A antikoerper, LILRB4 antikoerper, Lilrb4a antikoerper

Hintergrund: Synonyms:LILRB4, CD85K, ILT-3, ILT3, LIR-5, LIR5 Background:This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 49 kDa

UniProt: Q8NHJ6