eIF4EBP1 Antikörper (AA 1-118)

Produktnummer ABIN7113970

Dieses Maus Monoklonal-Antikörper erkennt spezifisch eIF4EBP1 in WB, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für eIF4EBP1 Antikörper (AA 1-118) (ABIN7113970)

Target: eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser eIF4EBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Klon: 6C4

Produktdetails anti-eIF4EBP1 Antikörper

Bindungsspezifität: AA 1-118

Verwendungszweck: EIF4EBP1 antibody

Aufreinigung: Protein A+G purification

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-118aa

Immunogen: eukaryotic translation initiation factor 4E binding protein 1

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu eIF4EBP1

Target: eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Andere Bezeichnung: EIF4EBP1

Hintergrund:

Synonyms: Eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1, eIF4E-binding protein 1)|Phosphorylated heat- and acid-stable protein regulated by insulin 1 (PHAS-I)|EIF4EBP1

Background: Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.

Molekulargewicht: 12 kDa

Gen-ID: 1978

UniProt: Q13541

Pathways: MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Regulation of Cell Size, BCR Signaling