fb16c04 antikoerper, wu:fb16c04 antikoerper, zgc:77714 antikoerper, MGC68415 antikoerper, CTDSP2 antikoerper, OS4 antikoerper, PSR2 antikoerper, SCP2 antikoerper, AI586070 antikoerper, D10Ertd73e antikoerper, OS-4 antikoerper, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 antikoerper, CTD small phosphatase 2 L homeolog antikoerper, CTD small phosphatase 2 antikoerper, ctdsp2 antikoerper, ctdsp2.L antikoerper, CTDSP2 antikoerper, Ctdsp2 antikoerper
Hintergrund
Synonyms:NIF2, OS4, SCP2 Background:Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain(CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.