ZC3HC1 Antikörper

Produktnummer ABIN7076278

Produktdetails anti-ZC3HC1 Antikörper

Target: ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZC3HC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse NIPA

Anwendungsinformationen

Applikationshinweise: WB (H) 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu ZC3HC1

Target: ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))

Andere Bezeichnung: NIPA (ZC3HC1 Produkte)

Synonyme: 1110054L24Rik antikoerper, AU018540 antikoerper, AU019789 antikoerper, HSPC216 antikoerper, Nipa antikoerper, NIPA antikoerper, RGD1561099 antikoerper, zinc finger, C3HC type 1 antikoerper, zinc finger C3HC-type containing 1 antikoerper, zinc finger, C3HC-type containing 1 antikoerper, Zc3hc1 antikoerper, ZC3HC1 antikoerper

Hintergrund: The regulated oscillation of protein expression is an essential mechanism of cell cycle control. The SCF class of E3 ubiquitin ligases is involved in this process by targeting cell cycle regulatory proteins for degradation by the proteasome, with the F-box subunit of the SCF specifically recruiting a given substrate to the SCF core. NIPA (nuclear interaction partner of ALK) is a human F-box-containing protein that defines an SCF-type E3 ligase (SCFNIPA) controlling mitotic entry. Assembly of this SCF complex is regulated by cell-cycle-dependent phosphorylation of NIPA, which restricts substrate ubiquitination activity to interphase.

Molekulargewicht: 55 kDa

Gen-ID: 232679

NCBI Accession: NP_001298015

UniProt: Q80YV2