TOR1AIP2 Antikörper

Produktnummer ABIN7075941

Produktdetails anti-TOR1AIP2 Antikörper

Target: TOR1AIP2 (Torsin A Interacting Protein 2 (TOR1AIP2))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOR1AIP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse TOR1AIP2

Anwendungsinformationen

Applikationshinweise: WB (M,R) 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu TOR1AIP2

Target: TOR1AIP2 (Torsin A Interacting Protein 2 (TOR1AIP2))

Andere Bezeichnung: TOR1AIP2 (TOR1AIP2 Produkte)

Synonyme: IFRG15 antikoerper, LULL1 antikoerper, NET9 antikoerper, RP11-12M5.5 antikoerper, 1110020D10Rik antikoerper, 15kDa antikoerper, A130072J07 antikoerper, AA103493 antikoerper, AW060462 antikoerper, AW610675 antikoerper, C77739 antikoerper, Ifrg15 antikoerper, Lull1 antikoerper, torsin 1A interacting protein 2 antikoerper, torsin-1A-interacting protein 2 antikoerper, torsin A interacting protein 2 antikoerper, torsin-1A-interacting protein 2, isoform IFRG15 antikoerper, TOR1AIP2 antikoerper, LOC610310 antikoerper, LOC100050862 antikoerper, LOC100338750 antikoerper, LOC100385418 antikoerper, LOC100595243 antikoerper, Tor1aip2 antikoerper

Hintergrund: LULL1 is a 470 amino acid endoplasmic reticulum single-pass membrane protein belonging to the TOR1AIP family. LULL1 interacts with torsinA, an essential AAA+ ATPase found in the endoplasmic reticulum (ER) and nuclear envelope (NE) of higher eukaryotes. LULL1 regulates the distribution and activity of torsinA within the ER and NE lumen and reveals functional defects in mutant torsinA, which is responsible for DYT1 dystonia, a neurodevelopmental disease caused by an in-frame deletion (Deltagag) in the gene encoding torsinA. The gene encoding LULL1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome.

Molekulargewicht: 58 kDa

Gen-ID: 240832

NCBI Accession: NP_001153652

UniProt: Q9ER81