TTC7A Antikörper

Produktnummer ABIN7075875

Produktdetails anti-TTC7A Antikörper

Target: TTC7A (Tetratricopeptide Repeat Domain 7A (TTC7A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTC7A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse TTC7A

Anwendungsinformationen

Applikationshinweise: WB (H) 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu TTC7A

Target: TTC7A (Tetratricopeptide Repeat Domain 7A (TTC7A))

Andere Bezeichnung: TTC7A (TTC7A Produkte)

Synonyme: 1110035E02Rik antikoerper, 1700007L07Rik antikoerper, Ttc7a antikoerper, fsn antikoerper, hea antikoerper, MINAT antikoerper, TTC7 antikoerper, Ttc7 antikoerper, tetratricopeptide repeat domain 7 antikoerper, tetratricopeptide repeat domain 7A antikoerper, Ttc7 antikoerper, TTC7A antikoerper, Ttc7a antikoerper

Hintergrund: TTC7A (TPR repeat protein 7A) is expressed in enterocytes within the duodenum, ileum, and colon, and has a role in enterocyte survival and function. Mutations in the TTC7A gene can result in a spectrum of intestinal disease, including multiple intestinal atresia (MIA) and very early onset inflammatory bowel diseases (VEOIBD). Functional analysis revealed that TTC7A binds to and facilitates the transport of PI4KIIIa from the trans-Golgi to the plasma membrane, while loss of TTC7A results in dysregulation of PI4KIIIa signaling. This antibody specially recognizes endogenous TTC7A.

Molekulargewicht: 100 kDa

Gen-ID: 225049

NCBI Accession: NP_082915

UniProt: Q8BGB2

Pathways: Transition Metal Ion Homeostasis