Nth Endonuclease III-Like 1 (NTHL1) Antikörper

Produktnummer ABIN7074866

Produktdetails

Target: Nth Endonuclease III-Like 1 (NTHL1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse NTH1

Anwendungsinformationen

Applikationshinweise: WB (H) 1:1000-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Antigendetails

Target: Nth Endonuclease III-Like 1 (NTHL1)

Andere Bezeichnung: NTH1 (NTHL1 Produkte)

Synonyme: psmc3 antikoerper, psmc3-a antikoerper, nth-like DNA glycosylase 1 S homeolog antikoerper, nthl1.S antikoerper

Hintergrund: NTHL1, also named as Endonuclease III-like protein 1 or OCTS3, is a 312 amino acid protein, which belongs to the Nth/MutY family. NTHL1 localizes in the nucleus and is widely expressed with highest levels in heart and lowest levels in lung and liver. NTHL1 Has both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity and incises damaged DNA at cytosines, thymines and guanines. NTHL1 acts on a damaged strand, 5' from the damaged site and is required for the repair of both oxidative DNA damage and spontaneous mutagenic lesions.

Molekulargewicht: 34 kDa

Gen-ID: 18207

NCBI Accession: NP_032769

UniProt: O35980