Nectin-1 (NECTIN1) Antikörper

Produktnummer ABIN7074789

Produktdetails

Target: Nectin-1 (NECTIN1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse PVRL1/NECTIN1

Anwendungsinformationen

Applikationshinweise: WB (H) 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Antigendetails

Target: Nectin-1 (NECTIN1)

Andere Bezeichnung: PVRL1/NECTIN1

Synonyme: CD111 antikoerper, CLPED1 antikoerper, ED4 antikoerper, HIgR antikoerper, HVEC antikoerper, OFC7 antikoerper, PRR antikoerper, PRR1 antikoerper, PVRR antikoerper, PVRR1 antikoerper, SK-12 antikoerper, nectin-1 antikoerper, nectin cell adhesion molecule 1 antikoerper, NECTIN1 antikoerper

Hintergrund: This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region. This protein acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome as well as non-syndromic cleft lip with or without cleft palate.

Molekulargewicht: 57 kDa

Gen-ID: 58235

NCBI Accession: NP_067399

UniProt: Q9JKF6