Deltex Homolog 1 Antikörper

Produktnummer ABIN7073794

Produktdetails anti-Deltex Homolog 1 Antikörper

Target: Deltex Homolog 1 (DTX1) (E3 Ubiquitin-protein ligase DTX1 (DTX1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Deltex Homolog 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse DTX1

Anwendungsinformationen

Applikationshinweise: IHC/IF (H,M,R) 1:600-1:1200/1:200-1:600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu Deltex Homolog 1

Target: Deltex Homolog 1 (DTX1) (E3 Ubiquitin-protein ligase DTX1 (DTX1))

Andere Bezeichnung: DTX1 (DTX1 Produkte)

Synonyme: hDx-1 antikoerper, Fxit1 antikoerper, mKIAA4160 antikoerper, deltex antikoerper, dtx antikoerper, xdtx1 antikoerper, deltex E3 ubiquitin ligase 1 antikoerper, deltex homolog 1 (Drosophila) antikoerper, deltex 1, E3 ubiquitin ligase antikoerper, deltex 1 L homeolog antikoerper, deltex 1 S homeolog antikoerper, DTX1 antikoerper, dtx1 antikoerper, Dtx1 antikoerper, dtx1.L antikoerper, dtx1.S antikoerper

Hintergrund: The Deltex homolog 1 (E3 ubiquitin-protein ligase DTX1) functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context.

Gen-ID: 14357

NCBI Accession: NP_032078

UniProt: Q61010

Pathways: Notch Signalweg