PCDHA12 Antikörper

Produktnummer ABIN7264547

Produktdetails anti-PCDHA12 Antikörper

Target: PCDHA12 (Protocadherin alpha 12 (PCDHA12))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHA12 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human PCDHA12 (NP_114070.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PCDHA12

Target: PCDHA12 (Protocadherin alpha 12 (PCDHA12))

Andere Bezeichnung: PCDHA12 (PCDHA12 Produkte)

Synonyme: PCDH-ALPHA12 antikoerper, Pcdha11 antikoerper, rCNRv12 antikoerper, Cnr5 antikoerper, Crnr5 antikoerper, Pcdha13 antikoerper, CNRv12 antikoerper, PCDHA12 antikoerper, protocadherin alpha 12 antikoerper, protocadherin alpha-12 antikoerper, PCDHA12 antikoerper, Pcdha12 antikoerper, LOC102147933 antikoerper

Hintergrund: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Gen-ID: 56137

UniProt: Q9UN75