ELAC2 Antikörper

Produktnummer ABIN7263113

Produktdetails anti-ELAC2 Antikörper

Target: ELAC2 (ElaC Homolog 2 (ELAC2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELAC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human ELAC2 (NP_776065.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ELAC2

Target: ELAC2 (ElaC Homolog 2 (ELAC2))

Andere Bezeichnung: ELAC2 (ELAC2 Produkte)

Synonyme: 1110017O07Rik antikoerper, D11Wsu80e antikoerper, Hpc2 antikoerper, ELC2 antikoerper, HPC2 antikoerper, elaC ribonuclease Z 2 antikoerper, ELAC2 antikoerper, Elac2 antikoerper

Hintergrund: The protein encoded by this gene has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 105 kDa

Calculated_MW: 50 kDa/56 kDa/87 kDa/92 kDa

Gen-ID: 60528

UniProt: Q9BQ52