ATP2B2 Antikörper

Produktnummer ABIN7262773

Produktdetails anti-ATP2B2 Antikörper

Target: ATP2B2 (ATPase, Ca++ Transporting, Plasma Membrane 2 (ATP2B2))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP2B2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human ATP2B2 (NP_001674.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ATP2B2

Target: ATP2B2 (ATPase, Ca++ Transporting, Plasma Membrane 2 (ATP2B2))

Andere Bezeichnung: ATP2B2 (ATP2B2 Produkte)

Synonyme: PMCA2 antikoerper, PMCA2a antikoerper, PMCA2i antikoerper, ATP2B4 antikoerper, ATP2B2 antikoerper, PMCA antikoerper, D6Abb2e antikoerper, Tmy antikoerper, dfw antikoerper, jog antikoerper, wms antikoerper, wri antikoerper, ATPase plasma membrane Ca2+ transporting 2 antikoerper, ATPase, Ca++ transporting, plasma membrane 2 antikoerper, ATP2B2 antikoerper, Atp2b2 antikoerper, atp2b2 antikoerper

Hintergrund: The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molekulargewicht:

Observed_MW: 137 kDa

Calculated_MW: 127-136 kDa

Gen-ID: 491

UniProt: Q01814

Pathways: Sensory Perception of Sound, Regulation of Cell Size, Ribonucleoside Biosynthetic Process