PEX5 Antikörper

Produktnummer ABIN7261734

Produktdetails anti-PEX5 Antikörper

Target: PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PEX5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human PEX5 (NP_000310.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PEX5

Target: PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))

Andere Bezeichnung: PEX5 (PEX5 Produkte)

Synonyme: AW212715 antikoerper, ESTM1 antikoerper, PTS1R antikoerper, Pxr1 antikoerper, X83306 antikoerper, PTS1-BP antikoerper, PBD2A antikoerper, PBD2B antikoerper, PXR1 antikoerper, Peroxin-5 antikoerper, peroxisomal biogenesis factor 5 antikoerper, pex5 antikoerper, Pex5 antikoerper, PEX5 antikoerper

Hintergrund: The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.

Gen-ID: 5830

UniProt: P50542

Pathways: Monocarboxylic Acid Catabolic Process