TCEB1 Antikörper

Produktnummer ABIN7260037

Produktdetails anti-TCEB1 Antikörper

Target: TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCEB1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human TCEB1 (NP_001191791.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TCEB1

Target: TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))

Andere Bezeichnung: TCEB1 (TCEB1 Produkte)

Synonyme: 2610043E24Rik antikoerper, 2610301I15Rik antikoerper, AA407206 antikoerper, AI987979 antikoerper, AW049146 antikoerper, SIII antikoerper, eloC antikoerper, TCEB1 antikoerper, fb09f09 antikoerper, wu:fb09f09 antikoerper, zgc:111990 antikoerper, zgc:92635 antikoerper, elongin C antikoerper, elongin C L homeolog antikoerper, transcription elongation factor B (SIII), polypeptide 1b antikoerper, Eloc antikoerper, eloc.L antikoerper, ELOC antikoerper, tceb1b antikoerper

Hintergrund: This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified.

Gen-ID: 6921

UniProt: Q15369

Pathways: SARS-CoV-2 Protein Interaktom