THRB Antikörper

Produktnummer ABIN7258710

Produktdetails anti-THRB Antikörper

Target: THRB (Thyroid Hormone Receptor, beta (THRB))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser THRB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human THRB (NP_000452.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu THRB

Target: THRB (Thyroid Hormone Receptor, beta (THRB))

Andere Bezeichnung: THRB (THRB Produkte)

Synonyme: C-ERBA-2 antikoerper, C-ERBA-BETA antikoerper, ERBA2 antikoerper, GRTH antikoerper, NR1A2 antikoerper, PRTH antikoerper, THR1 antikoerper, THRB1 antikoerper, THRB2 antikoerper, Nr1a2 antikoerper, T3R[b] antikoerper, T3Rbeta antikoerper, Thrb1 antikoerper, Thrb2 antikoerper, c-erbAbeta antikoerper, TR-beta antikoerper, TR[b]1 antikoerper, fj24f03 antikoerper, trb antikoerper, wu:fj24f03 antikoerper, CTR BETA 2 antikoerper, TR-BETA antikoerper, LOC734147 antikoerper, thrb antikoerper, THRB antikoerper, C-erba-beta antikoerper, RATT3REC antikoerper, T3rec antikoerper, TRbeta antikoerper, THR antikoerper, TRbeta1 antikoerper, thyroid hormone receptor beta antikoerper, thyroid hormone receptor, beta antikoerper, thyroid hormone receptor, beta S homeolog antikoerper, thyroid hormone receptor, beta L homeolog antikoerper, THRB antikoerper, Thrb antikoerper, thrb antikoerper, thrb.S antikoerper, thrb.L antikoerper

Hintergrund: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene.

Molekulargewicht:

Observed_MW: 53 kDa

Calculated_MW: 52 kDa/54 kDa

Gen-ID: 7068

UniProt: P10828

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound