MOCOS Antikörper

Produktnummer ABIN7257806

Produktdetails anti-MOCOS Antikörper

Target: MOCOS (Molybdenum Cofactor Sulfurase (MOCOS))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MOCOS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human MOCOS (NP_060417.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MOCOS

Target: MOCOS (Molybdenum Cofactor Sulfurase (MOCOS))

Andere Bezeichnung: MOCOS (MOCOS Produkte)

Synonyme: HMCS antikoerper, MCS antikoerper, MOS antikoerper, 1110018O12Rik antikoerper, DDBDRAFT_0217046 antikoerper, DDBDRAFT_0252757 antikoerper, DDB_0217046 antikoerper, DDB_0252757 antikoerper, Og antikoerper, im:7142948 antikoerper, mocos antikoerper, molybdenum cofactor sulfurase antikoerper, MOCOS antikoerper, Mocos antikoerper, AOR_1_1090144 antikoerper, mocos antikoerper, MCYG_05594 antikoerper, VDBG_04857 antikoerper, MGYG_02684 antikoerper, TERG_06775 antikoerper, mal antikoerper

Hintergrund: This gene encodes an enzyme that sulfurates the molybdenum cofactor which is required for activation of the xanthine dehydrogenase (XDH) and aldehyde oxidase (AO) enzymes. XDH catalyzes the conversion of hypoxanthine to uric acid via xanthine, as well as the conversion of allopurinol to oxypurinol, and pyrazinamide to 5-hydroxy pyrazinamide. Mutations in this gene cause the metabolic disorder classical xanthinuria type II which is characterized by the loss of XDH/XO and AO enzyme activity, decreased levels of uric acid in the urine, increased levels of xanthine and hypoxanthine in the serum and urine, formation of xanthine stones in the urinary tract, and myositis due to tissue deposition of xanthine.

Molekulargewicht:

Observed_MW: 98 kDa

Calculated_MW: 98 kDa

Gen-ID: 55034

UniProt: Q96EN8

Pathways: Response to Water Deprivation, ER-Nucleus Signaling