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ZNF828 Antikörper

ZNF828 Reaktivität: Human, Maus IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7255730
  • Target Alle ZNF828 Antikörper anzeigen
    ZNF828 (Zinc Finger Protein 828 (ZNF828))
    Reaktivität
    • 37
    • 21
    • 16
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 35
    • 2
    Kaninchen
    Klonalität
    • 37
    Polyklonal
    Konjugat
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ZNF828 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 13
    • 13
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human CHAMP1 (NP_115812.1).
    Isotyp
    IgG
    Top Product
    Discover our top product ZNF828 Primärantikörper
  • Applikationshinweise
    IF 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ZNF828 (Zinc Finger Protein 828 (ZNF828))
    Andere Bezeichnung
    CHAMP1 (ZNF828 Produkte)
    Synonyme
    ZNF828 antikoerper, C13orf8 antikoerper, CAMP antikoerper, CHAMP antikoerper, AA675043 antikoerper, AI116001 antikoerper, D8Ertd457e antikoerper, D8Ertd569e antikoerper, Zfp828 antikoerper, Znf828 antikoerper, mKIAA1802 antikoerper, chromosome alignment maintaining phosphoprotein 1 antikoerper, CHAMP1 antikoerper, Champ1 antikoerper
    Hintergrund
    CHAMP1 (chromosome alignment maintaining phosphoprotein 1), also known as ZNF828 or C13orf8, is a 812 amino acid protein containing one C2H2-type zinc finger. CHAMP1 is required for the proper alignment of chromosomes during metaphase, undergoing CDK1-dependent phosphorylation at multiple sites during mitosis. The phosphorylation counteracts the negative chromosomal alignment regulation of the zinc-finger domain of CHAMP1. One region of CHAMP1, the FPE region, is responsible for spindle and kinetochore localization, which is essential for proper chromosome alignment. CHAMP1 interacts with MAD2L2, PGOZ, CBX1, CBX3 and CBX5, and may recruit CENPE and CENPF to the kinetochore. The CHAMP1 gene is located on chromosome 13 and is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat and chicken.
    Gen-ID
    283489
    UniProt
    Q96JM3
    Pathways
    Maintenance of Protein Location
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