Meprin B Antikörper

Produktnummer ABIN7255141

Produktdetails anti-Meprin B Antikörper

Target: Meprin B (MEP1B) (Meprin A, beta (MEP1B))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Meprin B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human MEP1B (NP_005916.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Meprin B

Target: Meprin B (MEP1B) (Meprin A, beta (MEP1B))

Andere Bezeichnung: MEP1B (MEP1B Produkte)

Synonyme: MEP1B antikoerper, si:ch211-191a24.6 antikoerper, zgc:153272 antikoerper, Mep-1b antikoerper, meprin A subunit beta antikoerper, meprin A, beta antikoerper, meprin 1 beta antikoerper, MEP1B antikoerper, LOC100031050 antikoerper, mep1b antikoerper, LOC100545010 antikoerper, Mep1b antikoerper

Hintergrund: Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.

Molekulargewicht:

Observed_MW: 105 kDa

Calculated_MW: 79 kDa

Gen-ID: 4225

UniProt: Q16820