VNN1 Antikörper

Produktnummer ABIN7254229

Produktdetails anti-VNN1 Antikörper

Target: VNN1 (Vanin 1 (VNN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VNN1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of human VNN1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1: 100-1:500, ELISA 1:5000-1:240000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.7 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu VNN1

Target: VNN1 (Vanin 1 (VNN1))

Andere Bezeichnung: VNN1 (VNN1 Produkte)

Synonyme: HDLCQ8 antikoerper, Tiff66 antikoerper, V-1 antikoerper, hdlcq8 antikoerper, tiff66 antikoerper, vnn1.1 antikoerper, vanin-1 antikoerper, vanin 1 antikoerper, pantetheinase antikoerper, VNN1 antikoerper, Vnn1 antikoerper, vnn1 antikoerper, LOC100217969 antikoerper

Hintergrund: This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.

UniProt: O95497

Pathways: Negative Regulation of intrinsic apoptotic Signaling