CKMT1 Antikörper

Produktnummer ABIN7247918

Produktdetails anti-CKMT1 Antikörper

Target: CKMT1 (Creatine Kinase, Mitochondrial 1, Ubiquitous (CKMT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CKMT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of human CKMT1A/CKMT1B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.68 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CKMT1

Target: CKMT1 (Creatine Kinase, Mitochondrial 1, Ubiquitous (CKMT1))

Andere Bezeichnung: CKMT1A/CKMT1B (CKMT1 Produkte)

Synonyme: fb37h03 antikoerper, fb69a12 antikoerper, wu:fb37h03 antikoerper, wu:fb69a12 antikoerper, Mt-CK antikoerper, ScCKmit antikoerper, UbCKmit antikoerper, mi-CK antikoerper, Ckmt1 antikoerper, creatine kinase, mitochondrial 1 antikoerper, creatine kinase, mitochondrial 1, ubiquitous antikoerper, ckmt1 antikoerper, Ckmt1 antikoerper

Hintergrund: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 47 kDa

UniProt: P12532