DAZ1 Antikörper

Produktnummer ABIN7246199

Produktdetails anti-DAZ1 Antikörper

Target: DAZ1 (Deleted in Azoospermia 1 (DAZ1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAZ1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human DAZ1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:300, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.08 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DAZ1

Target: DAZ1 (Deleted in Azoospermia 1 (DAZ1))

Andere Bezeichnung: DAZ1 (DAZ1 Produkte)

Synonyme: DAZ1 antikoerper, DAZ4 antikoerper, DAZ antikoerper, SPGY antikoerper, deleted in azoospermia protein 1 antikoerper, deleted in azoospermia 1 antikoerper, LOC749905 antikoerper, DAZ1 antikoerper

Hintergrund: This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains three copies of the 10.8 kb repeat. However, no transcripts containing three copies of the RRM domain have been described, thus the RefSeq for this gene contains only two RRM domains.

UniProt: Q9NQZ3