EID1 Antikörper

Produktnummer ABIN7241222

Produktdetails anti-EID1 Antikörper

Target: EID1 (EP300 Interacting Inhibitor of Differentiation 1 (EID1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EID1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human EID1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu EID1

Target: EID1 (EP300 Interacting Inhibitor of Differentiation 1 (EID1))

Andere Bezeichnung: EID1 (EID1 Produkte)

Synonyme: C15orf3 antikoerper, CRI1 antikoerper, EID-1 antikoerper, IRO45620 antikoerper, PTD014 antikoerper, RBP21 antikoerper, 2610002K20Rik antikoerper, Cri1 antikoerper, ORF12 antikoerper, PNAS-22 antikoerper, RGD1562702 antikoerper, EP300 interacting inhibitor of differentiation 1 antikoerper, EID1 antikoerper, Eid1 antikoerper

Hintergrund: E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.

NCBI Accession: NP_055150

UniProt: Q9Y6B2