9230105K17Rik antikoerper, Bpifd1 antikoerper, BPIFD1 antikoerper, rBPI antikoerper, bpi antikoerper, bpi.L antikoerper, lbp antikoerper, bactericidal/permeability-increasing protein antikoerper, bactericidal permeablility increasing protein antikoerper, bactericidal/permeability-increasing protein S homeolog antikoerper, BPI antikoerper, Bpi antikoerper, bpi.S antikoerper
Hintergrund
This gene encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms. The cytotoxic action of BPI is limited to many species of Gram-negative bacteria, this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.