MT-ND6 Antikörper

Produktnummer ABIN7239227

Produktdetails anti-MT-ND6 Antikörper

Target: MT-ND6 (Mitochondrially Encoded NADH Dehydrogenase 6 (MT-ND6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MT-ND6 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human MT-ND6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.7 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MT-ND6

Target: MT-ND6 (Mitochondrially Encoded NADH Dehydrogenase 6 (MT-ND6))

Andere Bezeichnung: MT-ND6 (MT-ND6 Produkte)

Synonyme: MTND6 antikoerper, NADH6 antikoerper, mitochondrial NADH-ubiquinone oxidoreductase chain 6 antikoerper, NADH dehydrogenase, subunit 6 (complex I) antikoerper, NADH dehydrogenase subunit 6 antikoerper, NADH dehydrogenasesubunit 6 antikoerper, mt:ND6 antikoerper, ND6 antikoerper, nad6 antikoerper

Hintergrund: NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. The significance of NADH dehydrogenase subunit 6 (ND6) is rapidly becoming increasingly apparent as many mutations leading to amino acid changes in this subunit are associated with known mitochondrial diseases.

NCBI Accession: YP_003024037

UniProt: P03923