STIL Antikörper

Produktnummer ABIN7233972

Produktdetails anti-STIL Antikörper

Target: STIL (SCL/TAL1 Interrupting Locus (STIL))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STIL Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant Human SCL-interrupting locus protien

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu STIL

Target: STIL (SCL/TAL1 Interrupting Locus (STIL))

Andere Bezeichnung: STIL (STIL Produkte)

Synonyme: Sil antikoerper, MCPH7 antikoerper, SIL antikoerper, chunp6907 antikoerper, sill antikoerper, zgc:110502 antikoerper, STIL, centriolar assembly protein antikoerper, Scl/Tal1 interrupting locus antikoerper, STIL, centriolar assembly protein L homeolog antikoerper, scl/tal1 interrupting locus antikoerper, Stil antikoerper, STIL antikoerper, stil.L antikoerper, stil antikoerper

Hintergrund: This gene encodes a cytoplasmic protein implicated in regulation of the mitotic spindle checkpoint, a regulatory pathway that monitors chromosome segregation during cell division to ensure the proper distribution of chromosomes to daughter cells. The protein is phosphorylated in mitosis and in response to activation of the spindle checkpoint, and disappears when cells transition to G1 phase. It interacts with a mitotic regulator, and its expression is required to efficiently activate the spindle checkpoint. It is proposed to regulate Cdc2 kinase activity during spindle checkpoint arrest. Chromosomal deletions that fuse this gene and the adjacent locus commonly occur in T cell leukemias, and are thought to arise through illegitimate V-(D)-J recombination events. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: Q15468

Pathways: Tube Formation