MTOR Antikörper (AA 2226-2488)

Produktnummer ABIN7427519

Dieses Maus Monoklonal-Antikörper erkennt spezifisch MTOR in WB und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MTOR Antikörper (AA 2226-2488) (ABIN7427519)

Target: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MTOR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: D7

Produktdetails anti-MTOR Antikörper

Bindungsspezifität: AA 2226-2488

Verwendungszweck: Monoclonal Antibody to Serine/threonine-protein kinase mTOR (mTOR)

Spezifität: The antibody is a mouse monoclonal antibody raised against mTOR. It has been selected for its ability to recognize mTOR in immunohistochemical staining and western blotting.

Kreuzreaktivität: Schwein, Ratte

Aufreinigung: Protein A + Protein G affinity chromatography

Immunogen: Recombinant Serine/threonine-protein kinase mTOR (mTOR) corresdonding to Ala2226~Val2488 with N-terminal His Tag

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blotting: 0.01-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Kommentare:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 24 months

Details zu MTOR

Target: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Andere Bezeichnung: mTOR

Hintergrund: FRAP, FRAP1, FRAP2, MTOR, RAFT1, RAPT1, FK506 Binding Protein 12 Rapamycin Associated Protein, Mammalian Target Of Rapamycin, FKBP12-Rapamycin Complex-Associated Protein 1, Rapamycin and FKBP12 target

UniProt: P42345

Pathways: PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagie, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effekt