SLC1A7 Antikörper (C-Term)

Produktnummer ABIN6992100

Produktdetails anti-SLC1A7 Antikörper

Target: SLC1A7 (Solute Carrier Family 1 (Glutamate Transporter), Member 7 (SLC1A7))

Bindungsspezifität: AA 460-510, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC1A7 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: SLC1A7 antibody is human and mouse reactive. Multiple isoforms of SLC1A7 are known to exist.

Aufreinigung: SLC1A7 antibody is affinity chromatography purified via peptide column.

Immunogen: SLC1A7 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human SLC1A7. The immunogen is located within amino acids 460 - 510 of SLC1A7.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SLC1A7 antibody can be used for detection of SLC1A7 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SLC1A7 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SLC1A7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu SLC1A7

Target: SLC1A7 (Solute Carrier Family 1 (Glutamate Transporter), Member 7 (SLC1A7))

Andere Bezeichnung: SLC1A7 (SLC1A7 Produkte)

Synonyme: SLC1A7 antikoerper, si:ch211-284b7.1 antikoerper, slc1a7 antikoerper, A930031E15Rik antikoerper, Eaat5 antikoerper, AAAT antikoerper, EAAT5 antikoerper, solute carrier family 1 member 7 antikoerper, solute carrier family 1 (glutamate transporter), member 7a antikoerper, solute carrier family 1 (glutamate transporter), member 7 antikoerper, SLC1A7 antikoerper, slc1a7a antikoerper, Slc1a7 antikoerper

Hintergrund: The solute carrier family 1 member 7 (SLC1A7) protein was initially identified as a glutamate transporter coupled to a chloride conductance that is expressed primarily in the retina (1). More recent evidence indicates that is it widely expressed in peripheral tissues, also (2). Experiments have shown that SLC1A7 functions as a low-affinity/low-capacity glutamate transport, with an anion channel optimized for anion conductance in the negative voltage range (3). In the retina, SLC1A7 co-localizes with the serum and glucocorticoid dependent kinase SGK1, and its cell surface expression and activity is regulated SGK1 and its isoform SGK3 (4).

Molekulargewicht: Predicted: 17, 52, 62, 68 kDa

Observed: 52 kDa

Gen-ID: 6512

NCBI Accession: NP_001274524

UniProt: O00341

Pathways: Dicarboxylic Acid Transport