Puumala virus glycoprotein antibody is affinity chromatography purified via peptide column.
Immunogen
Puumala virus glycoprotein antibody was raised against a 19 amino acid peptide near the amino terminus of the Puumala virus glycoprotein. The immunogen is located within amino acids 90 - 140 of Puumala Virus Glycoprotein.
Puumala virus glycoprotein antibody can detect 10 ng Puumala virus glycoprotein peptide in ELISA at 1 μ,g/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Puumala virus glycoprotein antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
Puumala virus glycoprotein antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target
Glycoprotein (GPC)
Andere Bezeichnung
Puumala Virus Glycoprotein
Substanzklasse
Viral Protein
Hintergrund
Puumala virus (PUUV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) and is highly homologous to the protype hantavirus Hantaan virus (1). Like other hantaviruses, the PUUV glycoprotein is synthesized as a precursor that is posttranslationally processed into two glycoproteins G1 (Gn) and G2 (Gc). These glycoproteins interact with the PUUV nucleocapsid (NP) protein through their cytoplasmic tail, and this association has been suggested to be crucial to the binding of the ribonucleoprotein of the PUUV and the assembly of the virus particle (2).