Sin Nombre virus nucleocapsid antibody is affinity chromatography purified via peptide column.
Immunogen
Sin Nombre virus nucleocapsid antibody was raised against a 19 amino acid peptide near the center of the Sin Nombre virus nucleocapsid. The immunogen is located within amino acids 170 - 220 of Sin Nombre Virus Nucleocapsid.
Sin Nombre virus nucleocapsid antibody can detect 10 ng Sin Nombre virus nucleocapsid peptide in ELISA at 1 μ,g/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Sin Nombre virus nucleocapsid antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
Sin Nombre Nucleocapsid antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target
Sin Nombre Virus Nucleocapsid
Substanzklasse
Viral Protein
Hintergrund
Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) (1). The hantavirus nucleocapsid protein plays several roles in viral replication and assembly, and is the major antigen in humoral responses in humans and mice (2). Within the bunyviridae family, the nucleocapsid protein also functions as an RNA chaperone facilitating the formation of the stable genomic RNA ""panhandle"" and is thought to aid in the replication of bunyavirus RNA (3).