APPBP2 Antikörper (C-Term)

Produktnummer ABIN6991929

Produktdetails anti-APPBP2 Antikörper

Target: APPBP2 (Amyloid beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2 (APPBP2))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APPBP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Spezifität: APPBP2 antibody is human, mouse and rat reactive. At least two isoforms of APPBP2 are known to exist, this antibody will detect both isoforms.

Aufreinigung: APPBP2 antibody is affinity chromatography purified via peptide column.

Immunogen: APPBP2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human APPBP2. The immunogen is located within the last 50 amino acids of APPBP2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: APPBP2 antibody can be used for detection of APPBP2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: APPBP2 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: APPBP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu APPBP2

Target: APPBP2 (Amyloid beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2 (APPBP2))

Andere Bezeichnung: APPBP2 (APPBP2 Produkte)

Synonyme: HS.84084 antikoerper, PAT1 antikoerper, 1300003O07Rik antikoerper, AI465480 antikoerper, zgc:76971 antikoerper, wu:fb78e11 antikoerper, wu:fc25c09 antikoerper, APPBP2 antikoerper, DKFZp459F0530 antikoerper, amyloid beta precursor protein binding protein 2 antikoerper, amyloid beta precursor protein (cytoplasmic tail) binding protein 2 antikoerper, amyloid beta precursor protein (cytoplasmic tail) binding protein 2 S homeolog antikoerper, APPBP2 antikoerper, Appbp2 antikoerper, appbp2 antikoerper, appbp2.S antikoerper

Hintergrund: The amyloid beta precursor protein (cytoplasmic tail) binding protein 2 (APPBP2), also known as PAT1, interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing (1). The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease (2). APPBP2 has been found to be highly expressed in breast cancer (3).

Molekulargewicht: Predicted: 64 kDa

Observed: 57 kDa

Gen-ID: 10513

NCBI Accession: NP_006371

UniProt: Q92624