KANK3 Antikörper (N-Term)

Produktnummer ABIN6991853

Produktdetails anti-KANK3 Antikörper

Target: KANK3 (KN Motif and Ankyrin Repeat Domains 3 (KANK3))

Bindungsspezifität: AA 50-100, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KANK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Two alternatively spliced transcript variants encoding different isoforms have been identified.

Aufreinigung: KANK3 Antibody is affinity chromatography purified via peptide column.

Immunogen: KANK3 antibody was raised against an 18 amino acid peptide near the amino terminus of human KANK3 . The immunogen is located within amino acids 50 - 100 of KANK3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: KANK3 Antibody can be used for detection of KANK3 by Western blot starting at 1 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: KANK3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: KANK3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu KANK3

Target: KANK3 (KN Motif and Ankyrin Repeat Domains 3 (KANK3))

Andere Bezeichnung: KANK3 (KANK3 Produkte)

Synonyme: ANKRD47 antikoerper, 0610013D04Rik antikoerper, Ankrd47 antikoerper, D17Ertd288e antikoerper, NG28 antikoerper, RGD1308853 antikoerper, KN motif and ankyrin repeat domains 3 antikoerper, KANK3 antikoerper, Kank3 antikoerper

Hintergrund: KANK3 Antibody: Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. Like other members of the KANK family, KANK3 (KN motif and ankyrin repeat domain-containing protein 3), is thought to play a role in the formation of actin stress fibers. In zebrafish, the homolog of KANK3 interacts with the adaptor protein Numb, a protein implicated in multiple basic cellular processes, and is essential for epidermal integrity and neurulation, suggesting that KANK3 may play a similar role in higher organisms.

Molekulargewicht: Predicted: 90 kDa

Observed: 100 kDa

Gen-ID: 256949

NCBI Accession: NP_940873

UniProt: Q6NY19