WIPI1 Antikörper (C-Term)

Produktnummer ABIN6991756

Produktdetails anti-WIPI1 Antikörper

Target: WIPI1 (WD Repeat Domain, phosphoinositide Interacting 1 (WIPI1))

Bindungsspezifität: AA 350-400, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WIPI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Spezifität: At least two isoforms of WIPI1 are known to exist, this antibody will detect both isoforms.

Aufreinigung: WIPI1 Antibody is affinity chromatography purified via peptide column.

Immunogen: WIPI1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human WIPI1. The immunogen is located within amino acids 350 - 400 of WIPI1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WIPI1 antibody can be used for detection of Wipi1 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: WIPI1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: WIPI1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu WIPI1

Target: WIPI1 (WD Repeat Domain, phosphoinositide Interacting 1 (WIPI1))

Andere Bezeichnung: WIPI1 (WIPI1 Produkte)

Synonyme: ATG18 antikoerper, ATG18A antikoerper, WIPI49 antikoerper, 4930533H01Rik antikoerper, AW411817 antikoerper, D11Ertd498e antikoerper, RGD1307754 antikoerper, zgc:64205 antikoerper, WIPI1 antikoerper, atg18 antikoerper, wipi49 antikoerper, MGC145296 antikoerper, rgs9 antikoerper, wipi1 antikoerper, zgc:152760 antikoerper, WD repeat domain, phosphoinositide interacting 1 antikoerper, WD repeat domain, phosphoinositide interacting 1 S homeolog antikoerper, regulator of G protein signaling 9a antikoerper, WIPI1 antikoerper, Wipi1 antikoerper, wipi1 antikoerper, wipi1.S antikoerper, rgs9a antikoerper

Hintergrund: WIPI1 Antibody: WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as WIPI1, ATG18 or WIPI49, is thought to play a role in autophagy and may regulate protein trafficking in certain recycling pathways. It contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles and the trans-Golgi network. It is ubiquitously expressed with highest expression in heart, testis, placenta, pancreas and skeletal muscle. WIPI1 is upregulated in a variety of tumors, suggesting a role in carcinogenesis.

Molekulargewicht: 49 kDa

Gen-ID: 55062

NCBI Accession: NP_060453

UniProt: Q5MNZ9

Pathways: Nuclear Hormone Receptor Binding, ER-Nucleus Signaling