KCNK12 Antikörper (C-Term)

Produktnummer ABIN6991562

Produktdetails anti-KCNK12 Antikörper

Target: KCNK12 (Potassium Channel, Subfamily K, Member 12 (KCNK12))

Bindungsspezifität: AA 320-370, C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNK12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: KCNK12 antibody is predicted to not cross-react with other KCNK protein family members.

Aufreinigung: KCNK12 Antibody is affinity chromatography purified via peptide column.

Immunogen: KCNK12 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human KCNK12. The immunogen is located within amino acids 320 - 370 of KCNK12.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: KCNK12 antibody can be used for detection of KCNK12 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: KCNK12 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: KCNK12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu KCNK12

Target: KCNK12 (Potassium Channel, Subfamily K, Member 12 (KCNK12))

Andere Bezeichnung: KCNK12 (KCNK12 Produkte)

Synonyme: KCNK12 antikoerper, K2p12.1 antikoerper, THIK-2 antikoerper, THIK2 antikoerper, mntk1 antikoerper, potassium two pore domain channel subfamily K member 12 antikoerper, potassium channel, subfamily K, member 12 antikoerper, KCNK12 antikoerper, Kcnk12 antikoerper

Hintergrund: KCNK12 Antibody: KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK12 is expressed mainly in the brain and lung, but also observed in the kidneys, heart and skeletal muscle. KCNK12 is closely related to KCNK13 (58 % identity at the amino acid level), but could not yet been functionally expressed in vitro and may require other proteins to become active.

Gen-ID: 56660

NCBI Accession: NP_071338

UniProt: Q9HB15