Two isoforms of SLAMF1 are known to exist, this antibody will recognize both isoforms. SLAMF1 antibody is predicted to not cross-react with other SLAM protein family members.
Aufreinigung
SLAMF1 Antibody is affinity chromatography purified via peptide column.
Immunogen
SLAMF1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human SLAMF1. The immunogen is located within amino acids 30 - 80 of SLAMF1.
SLAMF1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
SLAMF1 antibody can be used for detection of SLAMF1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
SLAMF1 Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
SLAMF1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
SLAMF1
(Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
CD150 antikoerper, SLAM antikoerper, SLAMF1 antikoerper, 4933415F16 antikoerper, AA177906 antikoerper, CDw150 antikoerper, ESTM51 antikoerper, IPO-3 antikoerper, Slam antikoerper, RGD1560634 antikoerper, signaling lymphocytic activation molecule family member 1 antikoerper, SLAMF1 antikoerper, Slamf1 antikoerper
Hintergrund
SLAMF1 Antibody: The signaling lymphocyte-activation molecule family member 1 (SLAMF1) is a novel receptor on T cells that potentiates T cell expansion in a CD28-independent manner. SLAMF1 is predominantly expressed by hematopoietic tissues. Reports suggest that the extracellular domain of SLAMF1 is the receptor for the measles virus and acts as a co-activator on both T and B cells. It is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations of the SLAM associated gene may be associated with X-linked lympho-proliferative disease (XLP).