SLC39A13 Antikörper (N-Term)

Produktnummer ABIN6991460

Produktdetails anti-SLC39A13 Antikörper

Target: SLC39A13 (Solute Carrier Family 39 (Zinc Transporter), Member 13 (SLC39A13))

Bindungsspezifität: AA 150-200, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC39A13 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: At least two isoforms of ZIP13 are known to exist, this antibody will detect both isoforms. ZIP13 antibody is predicted to not cross-react with other ZIP family members.

Aufreinigung: ZIP13 Antibody is affinity chromatography purified via peptide column.

Immunogen: ZIP13 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human ZIP13. The immunogen is located within amino acids 150 - 200 of ZIP13.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ZIP13 antibody can be used for detection of ZIP13 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ZIP13 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ZIP13 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SLC39A13

Target: SLC39A13 (Solute Carrier Family 39 (Zinc Transporter), Member 13 (SLC39A13))

Andere Bezeichnung: ZIP13 (SLC39A13 Produkte)

Synonyme: 1100001L14Rik antikoerper, AA387663 antikoerper, ZIP13 antikoerper, solute carrier family 39 (metal ion transporter), member 13 antikoerper, solute carrier family 39 member 13 antikoerper, Slc39a13 antikoerper, SLC39A13 antikoerper

Hintergrund: ZIP13 Antibody: The zinc transporter ZIP13, also known as SLC39A13, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP13 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Mutations in ZIP13 have recently been shown to cause a spondylocheiro dysplastic form of Ehlers-Danlos syndrome (SCD-EDS), a generalized skeletal dysplasia involving mainly the spine with clinical abnormalities of the hands in addition to EDS-like features. Other experiments have shown that ZIP13 is required for proper connective tissue development and is involved in BMP/TGF- signaling pathways.

Gen-ID: 91252

NCBI Accession: NP_001121697

UniProt: Q96H72

Pathways: Transition Metal Ion Homeostasis