APBA2 Antikörper (AA 290-340)

Produktnummer ABIN6991437

Produktdetails anti-APBA2 Antikörper

Target: APBA2 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2))

Bindungsspezifität: AA 290-340

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APBA2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Aufreinigung: APBA2 Antibody is affinity chromatography purified via peptide column.

Immunogen: APBA2 antibody was raised against an 18 amino acid synthetic peptide near the center of human APBA2. The immunogen is located within amino acids 290 - 340 of APBA2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: APBA2 antibody can be used for detection of APBA2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: APBA2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: APBA2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu APBA2

Target: APBA2 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2))

Andere Bezeichnung: APBA2 (APBA2 Produkte)

Synonyme: MGC83599 antikoerper, D15S1518E antikoerper, HsT16821 antikoerper, LIN-10 antikoerper, MGC:14091 antikoerper, MINT2 antikoerper, X11-BETA antikoerper, X11L antikoerper, X11-like antikoerper, XllL antikoerper, mXllL antikoerper, Mint2 antikoerper, amyloid beta precursor protein binding family A member 2 antikoerper, amyloid beta (A4) precursor protein-binding, family A, member 2 L homeolog antikoerper, amyloid beta (A4) precursor protein-binding, family A, member 2 antikoerper, APBA2 antikoerper, apba2.L antikoerper, Apba2 antikoerper

Hintergrund: APBA2 Antibody: APBA2, a member of the X11 protein family, is a phosphotyrosine-binding domain protein and is a neuronal adapter protein that interacts with amyloid precursor protein (APP) and neuritic plaques in the brains of patients with Alzheimer's disease. It stabilizes APP and inhibits production of proteolytic APP fragments including the Abeta peptide that is deposited in the brains of Alzheimer's disease patients. APBA2 is believed to be involved in signal transduction processes and is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Recent reports suggest that it may also be a candidate gene for autism.

Gen-ID: 321

NCBI Accession: NP_005494

UniProt: Q99767

Pathways: Synaptic Vesicle Exocytosis