AP2M1 Antikörper (C-Term)

Produktnummer ABIN6991115

Produktdetails anti-AP2M1 Antikörper

Target: AP2M1 (Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))

Bindungsspezifität: AA 360-410, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser AP2M1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: AP2M1 Antibody is affinity chromatography purified via peptide column.

Immunogen: AP2M1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human AP2M1. The immunogen is located within amino acids 360 - 410 of AP2M1.

Isotyp: IgY

Anwendungsinformationen

Applikationshinweise: AP2M1 antibody can be used for detection of AP2M1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: AP2M1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: AP2M1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu AP2M1

Target: AP2M1 (Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))

Andere Bezeichnung: AP2M1 (AP2M1 Produkte)

Synonyme: AP50 antikoerper, CLAPM1 antikoerper, mu2 antikoerper, Ap50 antikoerper, Clapm1 antikoerper, cb34 antikoerper, Ap2m1 antikoerper, dpy-23 antikoerper, sb:cb34 antikoerper, zgc:55711 antikoerper, zgc:85653 antikoerper, wu:fa97a10 antikoerper, ap2m1-a antikoerper, ap2m1 antikoerper, zgc:56643 antikoerper, AP2M1 antikoerper, adaptor related protein complex 2 mu 1 subunit antikoerper, adaptor-related protein complex 2, mu 1 subunit antikoerper, adaptor-related protein complex 2, mu 1 subunit, a antikoerper, adaptor related protein complex 2 mu 1 subunit L homeolog antikoerper, adaptor-related protein complex 2, mu 1 subunit, b antikoerper, AP-2 complex subunit mu-1 antikoerper, clathrin coat assembly protein AP50 antikoerper, clathrin coat assembly protein ap50 antikoerper, AP2M1 antikoerper, Ap2m1 antikoerper, ap2m1a antikoerper, ap2m1.L antikoerper, ap2m1b antikoerper, ap2m1 antikoerper, cgd8_950 antikoerper, PY06523 antikoerper, PVX_118455 antikoerper, PVX_123590 antikoerper, CpipJ_CPIJ003697 antikoerper

Hintergrund: AP2M1 Antibody: The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist.

Gen-ID: 1173

NCBI Accession: NP_004059

UniProt: Q96CW1

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation, SARS-CoV-2 Protein Interaktom