Adenovirus 9 E4 Orf1 Antikörper (C-Term)

Produktnummer ABIN6990957

Produktdetails anti-Adenovirus 9 E4 Orf1 Antikörper

Target: Adenovirus 9 E4 Orf1 (HAdV-9 E4-ORF1) (Human Adenovirus type 9 E4 Orf1 (HAdV-9 E4-ORF1))

Bindungsspezifität: C-Term

Reaktivität: Human Adenovirus 9

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: ELISA

Aufreinigung: Adenovirus-9 E4 Orf1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Ad-9 E4 Orf1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of the Ad-9 E4 Orf1. The immunogen is located within the last 50 amino acids of Adenovirus-9 E4 Orf1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Ad-9 E4 Orf1 antibody can detect 10 ng Ad-9 E4 Orf1 peptide in ELISA at 1 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Adenovirus-9 E4 Orf1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Adenovirus-9 E4 Orf1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Adenovirus 9 E4 Orf1

Target: Adenovirus 9 E4 Orf1 (HAdV-9 E4-ORF1) (Human Adenovirus type 9 E4 Orf1 (HAdV-9 E4-ORF1))

Andere Bezeichnung: Adenovirus-9 E4 Orf1 (HAdV-9 E4-ORF1 Produkte)

Substanzklasse: Viral Protein

Hintergrund: Adenovirus-9 E4 Orf1 Antibody: The many different serotypes of human adenoviruses (Ad) are divided into six subgroups, of which all Ad subgroup A and B and two subgroup D Ads can elicit tumors in infected rodents. Unlike the Ads from subgroup A and B, the ones from subgroup D, Ad9 and Ad10 elicit estrogen-dependent mammary tumors as opposed to undifferentiated sarcomas. In the case of Ad9, its tumorigenicity is dependent on the product of the open reading frame (ORF) 1 of the early region 4 (E4). The tumorigenic potential of Ad9 E4 Orf1 depends on a carboxyl-terminal PDZ domain-binding motif that mediates interactions with several different membrane-associated cellular proteins such as MUPP1, PATJ, MAGI-1, ZO-2 and Dlg1. It has been suggested that Ad9 E4 Orf1 may have evolved from an ancestral cellular dUTP pyrophosphatase.

Gen-ID: 6386282

UniProt: P89079