GRIK3 Antikörper (N-Term)

Produktnummer ABIN6990822

Produktdetails anti-GRIK3 Antikörper

Target: GRIK3 (Glutamate Receptor, Ionotropic, Kainate 3 (GRIK3))

Bindungsspezifität: AA 30-80, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Grik3 Antibody is affinity chromatography purified via peptide column.

Immunogen: Grik3 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of the human Grik3. The immunogen is located within amino acids 30 - 80 of Grik3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Grik3 antibody can be used for detection of Grik3 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Grik3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Grik3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu GRIK3

Target: GRIK3 (Glutamate Receptor, Ionotropic, Kainate 3 (GRIK3))

Andere Bezeichnung: Grik3 (GRIK3 Produkte)

Synonyme: GRIK3 antikoerper, eaa5 antikoerper, glr7 antikoerper, glur7 antikoerper, 9630027E11 antikoerper, GluK3 antikoerper, GluR7-3 antikoerper, Glur-7 antikoerper, Glur7 antikoerper, GluR7 antikoerper, gluR-7 antikoerper, EAA5 antikoerper, GLR7 antikoerper, GLUR7 antikoerper, GluR7a antikoerper, glutamate ionotropic receptor kainate type subunit 3 antikoerper, glutamate receptor, ionotropic, kainate 3 L homeolog antikoerper, glutamate receptor, ionotropic, kainate 3 antikoerper, GRIK3 antikoerper, grik3.L antikoerper, Grik3 antikoerper

Hintergrund: Grik3 Antibody: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik3, also known as glutamate receptor 7, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik3 is highly homologous to the related ionotrophic glutamate receptors Grik2 and Grik1. Grik3 has recently been shown to be an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses as grik3-null mice show significantly reduced short- and long-term synaptic potentiation. Other reports have suggested that different polymorphisms in the Grik3 protein may be associated with neurological defects such as recurrent major depressive disorder and schizophrenia. This Grik3 antibody does not cross-react with Grik2.

Gen-ID: 2899

UniProt: Q13003

Pathways: Synaptic Membrane