TBC1D1 Antikörper (C-Term)

Produktnummer ABIN6990756

Produktdetails anti-TBC1D1 Antikörper

Target: TBC1D1 (TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1 (TBC1D1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TBC1D1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: TBC1D1 Antibody is affinity chromatography purified via peptide column.

Immunogen: TBC1D1 antibody was raised against a 22 amino acid synthetic peptide from near the carboxy terminus of human TBC1D1. The immunogen is located within the last 50 amino acids of TBC1D1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TBC1D1 antibody can be used for detection of TBC1D1 by Western blot at 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TBC1D1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TBC1D1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TBC1D1

Target: TBC1D1 (TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1 (TBC1D1))

Andere Bezeichnung: TBC1D1 (TBC1D1 Produkte)

Synonyme: TBC1D1 antikoerper, TBC antikoerper, TBC1 antikoerper, 1110062G02Rik antikoerper, AI385682 antikoerper, AW555803 antikoerper, Tbc1 antikoerper, mKIAA1108 antikoerper, TBC1 domain family member 1 antikoerper, TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 antikoerper, TBC1 domain family, member 1 antikoerper, TBC1D1 antikoerper, tbc1d1 antikoerper, LOC100523386 antikoerper, Tbc1d1 antikoerper

Hintergrund: TBC1D1 Antibody: TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain and presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2/USP6, yeast Bub2, and CDC16. TBC1D1 and TBC1D4 (AS160) have been demonstrated to be Rab GAPs (GTPase-activating proteins) that link upstream to Akt and phosphoinositide 3-kinase and downstream to Rabs involved in trafficking of GLUT4 vesicles. TBC1D1 regulates insulin-mediated GLUT4 translocation through its GAP activity, and is a likely Akt substrate. Mutations in the Tbc1d1 gene lead to some cases of severe human obesity.

Molekulargewicht: Predicted: 128 kDa

Observed: 140 kDa 

Gen-ID: 23216

NCBI Accession: NP_055988

UniProt: Q86TI0