TRPC3 Antikörper (N-Term)

Produktnummer ABIN6990665

Produktdetails anti-TRPC3 Antikörper

Target: TRPC3 (Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3))

Bindungsspezifität: AA 120-170, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRPC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody may cross-react with TRPC6 and TRPC7.

Aufreinigung: TRPC3 Antibody is affinity chromatography purified via peptide column.

Immunogen: TRPC3 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human TRPC3. The immunogen is located within amino acids 120 - 170 of TRPC3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TRPC3 antibody can be used for the detection of TRPC3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TRPC3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TRPC3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TRPC3

Target: TRPC3 (Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3))

Andere Bezeichnung: TRPC3 (TRPC3 Produkte)

Synonyme: TRPC3 antikoerper, Trpc3 antikoerper, TRP3 antikoerper, Mwk antikoerper, Trcp3 antikoerper, Trp3 antikoerper, Trrp3 antikoerper, TrpC3c antikoerper, transient receptor potential cation channel subfamily C member 3 antikoerper, transient receptor potential cation channel, subfamily C, member 3 antikoerper, TRPC3 antikoerper, Trpc3 antikoerper

Hintergrund: TRPC3 Antibody: The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the "canonical TRP" (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. TRPC3 encodes a Ca²⁺-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels.

Molekulargewicht: Predicted: 93 kDa

Observed: 100 kDa

Gen-ID: 7222

UniProt: Q13507