AIM (AA 60-110), (N-Term) Antikörper

Produktnummer ABIN6990636

Produktdetails

Target: AIM

Bindungsspezifität: AA 60-110, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Aufreinigung: AIM Antibody is affinity chromatography purified via peptide column.

Immunogen: AIM antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human AIM. The immunogen is located within amino acids 60 - 110 of AIM.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: AIM antibody can be used for the detection of AIM by Western blot at 1 - 4 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: AIM Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: AIM antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Antigendetails

Target: AIM

Synonyme: 5830438K24Rik antikoerper, AI452015 antikoerper, AIM antikoerper, VEA antikoerper, BL-AC/P26 antikoerper, CLEC2C antikoerper, EA1 antikoerper, GP32/28 antikoerper, MLR-3 antikoerper, CD69 antigen antikoerper, CD69 molecule antikoerper, Cd69 antikoerper, CD69 antikoerper

Hintergrund: AIM Antibody: Apoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that AIM functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. AIM was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant AIM significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that AIM functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection.

Gen-ID: 922

UniProt: O43866