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CD4 Antikörper (N-Term)

CD4 Reaktivität: Human, Maus, Ratte WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 8G1B12 unconjugated

Produktnummer ABIN6990334

Datenblatt (PDF)

Target Alle CD4 Antikörper anzeigen

CD4
Bindungsspezifität
28

16

16

16

16

9

7

6

5

4

4

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
Reaktivität
341

205

118

38

24

22

20

19

15

10

10

10

8

7

7

6

6

6

6

2

2

2

1

1

1

1
Human, Maus, Ratte
Wirt
333

137

119

4

2

1
Maus
Passende Sekundärantikörper
Klonalität
457

132

3
Monoklonal
Konjugat
184

64

55

48

29

15

14

12

12

10

10

9

7

7

7

7

5

5

5

5

5

5

5

5

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1
Dieser CD4 Antikörper ist unkonjugiert
Applikation
475

189

112

92

79

72

62

42

39

37

27

25

17

10

9

8

7

7

6

6

5

5

4

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung

CD4 Monoclonal Antibody is Protein A purified.

Immunogen

Mouse monoclonal CD4 antibody was raised against a 193 amino acid recombinant protein near the amino terminus of human CD4.

Klon

8G1B12

Isotyp

IgG1

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anti-CD4 (CD4) antibody
CD4 Reaktivität: Human, Maus, Ratte, Huhn, Affe, Schwein, Hund, Cat, Kaninchen, Rind (Kuh), Schaf, Meerschweinchen, Ziege, Pferd, Hamster, Esel, Avian WB Wirt: Ziege Polyclonal unconjugated

anti-CD4 (CD4) (AA 231-330) antibody
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anti-CD4 (CD4) (N-Term) antibody
CD4 Reaktivität: Human FACS, WB, CyTOF Wirt: Maus Monoclonal MEM-241 unconjugated

anti-CD4 (CD4) (AA 300-400) antibody
CD4 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

anti-CD4 (CD4) antibody
CD4 Reaktivität: Maus FACS, IP, IHC (fro), ICC, Func Wirt: Ratte Monoclonal GK1-5 unconjugated

anti-CD4 (CD4) (N-Term) antibody (FITC)
CD4 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-241 FITC

anti-CD4 (CD4) (AA 301-400) antibody
CD4 Reaktivität: Human, Maus, Ratte FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-CD4 (CD4) (N-Term) antibody (PE)
CD4 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-241 PE

anti-CD4 (CD4) antibody (PE)
CD4 Reaktivität: Ratte FACS Wirt: Maus Monoclonal OX-35 PE

Applikationshinweise

WB: 0.5-1 μ,g/mL, IHC: 5 μ,g/mL.

Antibody validated: Western Blot in human, mouse and rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

CD4 Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

CD4 monoclonal antibody can be stored at -20°C, stable for one year.
Target

CD4

Andere Bezeichnung

CD4 (CD4 Produkte)

Synonyme

cd4 antikoerper, L3T4 antikoerper, Ly-4 antikoerper, CD4mut antikoerper, W3/25 antikoerper, p55 antikoerper, CD4 molecule antikoerper, carcinoembryonic antigen-related cell adhesion molecule 5 antikoerper, T-cell surface glycoprotein CD4 antikoerper, CD4 antigen antikoerper, Cd4 molecule antikoerper, CD4 antikoerper, LOC100125525 antikoerper, cd4 antikoerper, Cd4 antikoerper

Hintergrund

CD4 Monoclonal Antibody: CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 Molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120.

Molekulargewicht

Predicted: 51kD

Observed: 51 kD kDa

Gen-ID

920

NCBI Accession

NP_000607

UniProt

P01730

Pathways

T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events