SARS-CoV-2 Spike Antikörper

Produktnummer ABIN6990096

Produktdetails anti-SARS-CoV-2 Spike Antikörper

Target: SARS-CoV-2 Spike

Reaktivität: SARS Coronavirus-2 (SARS-CoV-2)

Wirt: Human

Klonalität: Monoklonal

Konjugat: Dieser SARS-CoV-2 Spike Antikörper ist unkonjugiert

Applikation: ELISA

Spezifität: Antibody recognizes 2019-nCoV S-RBD Protein.

Reinheit: 95,00%

Immunogen: Cultured in vitro under conditions free from animal derived components.

Klon: 5E8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunoreactivity: 80-120 % compared to the reference sample in an ELISA test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 5.0 mg/mL

Buffer: PBS, pH 7.4

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: 24 months from manufacturing at <-20 °C, 1 month, 2 to 8 °C under sterile conditions.

Details zu SARS-CoV-2 Spike

Target: SARS-CoV-2 Spike

Abstract: SARS-CoV-2 Spike Produkte

Synonyme: E2 antikoerper, E2 glycoprotein precursor antikoerper, Surface Glycoprotein antikoerper, S antikoerper

Substanzklasse: Viral Protein

Hintergrund: The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Gen-ID: 43740568