GOT2 Antikörper

Produktnummer ABIN6989684

Produktdetails anti-GOT2 Antikörper

Target: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser GOT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Synthetic Peptide within Human GOT2.

Klon: 4H6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu GOT2

Target: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Andere Bezeichnung: GOT2 (GOT2 Produkte)

Synonyme: KAT4 antikoerper, KATIV antikoerper, mitAAT antikoerper, AI789014 antikoerper, Got-1 antikoerper, cAspAT antikoerper, cCAT antikoerper, AL022787 antikoerper, FABP-pm antikoerper, Got-2 antikoerper, mAspAT antikoerper, ASPATA antikoerper, got2 antikoerper, zgc:66329 antikoerper, fj40h07 antikoerper, wu:fj40h07 antikoerper, zgc:56425 antikoerper, glutamic-oxaloacetic transaminase 2 antikoerper, glutamic-oxaloacetic transaminase 1, soluble antikoerper, glutamatic-oxaloacetic transaminase 2, mitochondrial antikoerper, glutamic-oxaloacetic transaminase 2a, mitochondrial antikoerper, glutamic-oxaloacetic transaminase 2 L homeolog antikoerper, Aspartate amino transferase activity antikoerper, glutamic-oxaloacetic transaminase 2b, mitochondrial antikoerper, GOT2 antikoerper, got2 antikoerper, Got1 antikoerper, Got2 antikoerper, got2a antikoerper, got2.L antikoerper, AST antikoerper, got2b antikoerper

Hintergrund:

Synonyms: AATM_HUMAN antibody, AL022787 antibody, Aspartate aminotransferase 2 antibody, Aspartate aminotransferase antibody, Aspartate aminotransferase, mitochondrial antibody, Aspartate transaminase 2 antibody, ASPATA antibody, EC 2.6.1.1 antibody, FABP 1 antibody,

Background: GOT2 [Glutamate oxaloacetate transaminase] is a ubiquitous pyridoxal phosphate dependent enzyme which exists in both mitochondrial and cytosolic forms. The enzyme plays an important role in amino acid metabolism and in the urea and tricarboxylic acid cycles. The 2 isoenzymes are homodimeric. In liver about 80 % of the enzyme activity is mitochondrial in origin, whereas in serum the enzyme activity is largely cytosolic. Although the mitochondrial and soluble forms of GOT are coded by different chromosomes, the 2 show close homology in amino acid sequence and were presumably derived from a common ancestral gene. Serum GOT [with SGPT] levels are usually elevated in states of hepatocellular injury (injury to the liver cells), the highest levels are associated with hepatitis of a viral origin. High levels are also found after myocardial infarction, when SGPT levels are lower.

Gen-ID: 2806

UniProt: P00505

Pathways: Monocarboxylic Acid Catabolic Process