EIF3B Antikörper

Produktnummer ABIN6989663

Produktdetails anti-EIF3B Antikörper

Target: EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser EIF3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Synthetic Peptide within N terminal human eIF3B.

Klon: 5H10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu EIF3B

Target: EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))

Andere Bezeichnung: eIF3B (EIF3B Produkte)

Synonyme: EIF3-ETA antikoerper, EIF3-P110 antikoerper, EIF3-P116 antikoerper, EIF3S9 antikoerper, PRT1 antikoerper, AL033316 antikoerper, AL033334 antikoerper, AL033369 antikoerper, AW208965 antikoerper, D5Wsu45e antikoerper, Eif3s9 antikoerper, eif3-eta antikoerper, eif3-p110 antikoerper, eif3-p116 antikoerper, eif3s9 antikoerper, prt1 antikoerper, ATEIF3B-2 antikoerper, EIF3B antikoerper, EUKARYOTIC TRANSLATION INITIATION FACTOR 3B antikoerper, F18A17.30 antikoerper, F18A17_30 antikoerper, eukaryotic translation initiation factor 3B-2 antikoerper, DDBDRAFT_0218512 antikoerper, DDBDRAFT_0233929 antikoerper, DDB_0218512 antikoerper, DDB_0233929 antikoerper, eIF-3-eta antikoerper, eif3b antikoerper, wu:fc17c01 antikoerper, GB10123 antikoerper, eIF3b antikoerper, AO090005000892 antikoerper, CaO19.6584 antikoerper, eIF3 p90 antikoerper, eukaryotic translation initiation factor 3 subunit B antikoerper, eukaryotic translation initiation factor 3, subunit B antikoerper, eukaryotic translation initiation factor 3B-2 antikoerper, eukaryotic initiation factor antikoerper, RNA recognition motif-containing protein RRM antikoerper, eukaryotic translation initiation factor 3b antikoerper, eukaryotic translation initiation factor 3 subunit B L homeolog antikoerper, eukaryotic translation initiation factor 3, subunit Ba antikoerper, eukaryotic translation initiation factor 3 subunit 9 antikoerper, translation initiation factor eIF-3 subunit 9 antikoerper, Eukaryotic translation initiation factor 3 subunit B antikoerper, translation initiation factor eIF3 subunit b antikoerper, EIF3B antikoerper, Eif3b antikoerper, eif3b antikoerper, EIF3B-2 antikoerper, eIF3s9 antikoerper, eif3B antikoerper, eif3b.L antikoerper, eif3ba antikoerper, LOC410100 antikoerper, eIF3-S9 antikoerper, AOR_1_1564174 antikoerper, VDBG_02490 antikoerper, PGTG_13070 antikoerper, Tsp_02250 antikoerper, eif-3.B antikoerper, PRT1 antikoerper

Hintergrund:

Synonyms: eIF-3-eta antibody, eIF3 eta antibody, eIF3 p110 antibody, eIF3 p116 antibody, EIF3-ETA antibody, EIF3-P110 antibody, EIF3-P116 antibody, eIF3b antibody, EIF3B_HUMAN antibody, EIF3S9 antibody, EIF3S9, formerly antibody, Eukaryotic translation initiation factor 3, subunit B antibody, Eukaryotic translation initiation factor 3 subunit 9 antibody, eukaryotic translation initiation factor 3 subunit 9 eta antibody, Eukaryotic translation initiation factor 3 subunit B antibody, eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD) antibody, eukaryotic translation initiation factor 3, subunit 9 eta, 116 kDa antibody, eukaryotic translation initiation factor 3, subunit 9, formerly antibody, hPrt1 antibody, Protein synthesis defective at 36 degrees celsius 1, S. cerevisiae, homolog of antibody, PRT1 antibody, Prt1 homolog antibody

Background: eIF3b expression relates to human bladder and prostate cancer prognosis, is required for tumor growth, and thus a candidate therapeutic target.The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. Association of eIF3 proteins with the 40S ribosomal subunit stabilizes eIF2-GTP-Met-tRNAiMet complex association and mRNA binding, and promotes dissociation of 80S ribosomes into 40S and 60S subunits, thereby promoting the assembly of the pre-initiation complex. Overexpression of eIF3 proteins is common in several cancers, suggesting a role for eIF3 proteins in tumorigenesis.

Gen-ID: 8662

UniProt: P55884

Pathways: Ribonucleoprotein Complex Subunit Organization