VTCN1 Antikörper (AA 101-200)

Produktnummer ABIN6989287

Produktdetails anti-VTCN1 Antikörper

Target: VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))

Bindungsspezifität: AA 101-200

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VTCN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human B7H4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu VTCN1

Target: VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))

Andere Bezeichnung: B7H4 (VTCN1 Produkte)

Synonyme: B7h4 antikoerper, B7s1 antikoerper, B7x antikoerper, BC032925 antikoerper, B7-H4 antikoerper, B7H4 antikoerper, B7S1 antikoerper, B7X antikoerper, B7h.5 antikoerper, PRO1291 antikoerper, VCTN1 antikoerper, RGD1311204 antikoerper, V set domain containing T cell activation inhibitor 1 L homeolog antikoerper, V-set domain containing T cell activation inhibitor 1 antikoerper, V-set domain containing T-cell activation inhibitor 1 antikoerper, V set domain containing T cell activation inhibitor 1 antikoerper, vtcn1.L antikoerper, VTCN1 antikoerper, vtcn1 antikoerper, Vtcn1 antikoerper

Hintergrund:

Synonyms: B7-H4, B7h4, B7S1, B7x, BC032925, Immune costimulatory protein B7H4, MGC41287, PRO1291, T cell costimulatory molecule B7x, V set domain-containing T cell activation inhibitor 1, VCTN1, VTCN1_HUMAN.

Background: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.

Gen-ID: 79679

UniProt: Q7Z7D3